SCHEMBL3967293

SCHEMBL3967293

CCOC(=O)c1ccc(CC#N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA12 O43570 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
MAOA P21397 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
HPGD P15428 4/20 0.51
HTT P42858 3/20 0.51
ALDH1A1 P00352 2/20 0.51
HSP90AA1 P07900 1/20 0.51
CACNA1B Q00975 1/20 0.51
APBA1 Q02410 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4118009 0.89 KMT2A (0.64) CA1CA2CA12CA9LMNA
SCHEMBL9781942 0.84 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL7995893 0.84 ESR1 (0.62) ESR1LMNACYP1A2CYP3A4SMN1; SMN2
SCHEMBL12674759 0.83 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL2214078 0.83 CA12 (0.53) CA1CA2CA12CA7CA9
SCHEMBL378575 0.82 LOXL2 (0.59) CA1CA2CA12CA7CA9
SCHEMBL128190 0.81 CA1 (0.70) CA1CA2CA12CA7CA9
SCHEMBL87450 0.81 CA1 (0.83) CA1CA2CA12CA7CA9
SCHEMBL1198816 0.81 CYP4F2 (0.61) CA1CA2CA12CA7CA9
SCHEMBL12199135 0.80 CA1 (0.68) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398326-B2 Monoazo dichroic dye compound, polarizing plate composition comprising same, polarizing plate formed therefrom, and optical device comprising same LG CHEM, LTD. (KR) 2025-08-26 US disclosed
US-20230357638-A1 MONOAZO DICHROIC DYE COMPOUND, POLARIZING PLATE COMPOSITION COMPRISING SAME, POLARIZING PLATE FORMED THEREFROM, AND OPTICAL DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-11-09 US disclosed
US-20230357638-A1 MONOAZO DICHROIC DYE COMPOUND, POLARIZING PLATE COMPOSITION COMPRISING SAME, POLARIZING PLATE FORMED THEREFROM, AND OPTICAL DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-11-09 US disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 US disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 US disclosed
EP-4234552-A2 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF Raze Therapeutics, Inc. (US) 2023-08-30 EP disclosed
CN-116535285-A Photocatalytic benzyl position C (sp 3 ) Method for functionalization of Cl bonds and use thereof 中国科学院理化技术研究所 2023-08-04 CN disclosed
EP-3426244-B1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS INC (US) 2023-06-07 EP disclosed
EP-3426244-B1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS INC (US) 2023-06-07 EP disclosed
CN-116057429-A Monoazo dichroic dye compound, polarizing plate composition comprising the same, polarizing plate formed therefrom, and optical device comprising the same 株式会社LG化学 2023-05-02 CN disclosed
US-7423035-B2 Substituted cycloalkyl derivatives, process for the manufacture thereof and use thereof as medicament BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-09-09 US disclosed
US-20080146554-A1 Substituted Cycloalkyl Derivatives, Process for the Manufacture thereof and Use thereof as Medicament BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-06-19 US disclosed
US-7351719-B2 Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2008-04-01 US disclosed
US-20050261286-A1 Substituted cycloalkyl derivatives, process for the manufacture thereof and use thereof as medicament BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 US disclosed
US-20040242572-A1 New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-12-02 US disclosed
US-20040152742-A1 Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-08-05 US disclosed
EP-0303478-B1 IMPROVEMENTS IN OR RELATING TO LEUKOTRIENE ANTAGONISTS ELI LILLY AND COMPANY (US) 1992-09-30 EP disclosed
US-4820723-A FOR TREATMENT OF HYPERSENSITIVITY, ASTHMA, SHOCK OR CARDIOVASCULAR DISORDERS ELI LILLY AND COMPANY (US) 1989-04-11 US disclosed
EP-0303478-A1 Improvements in or relating to leukotriene antagonists ELI LILLY AND COMPANY (US) 1989-02-15 EP disclosed
US-4735959-A HYPOGLYCEMIC AGENTS DR. KARL THOMAE GMBH (DE) 1988-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF PHGDH, G6PD, PGD CA1 1552/4885CA2 806/4885CA12 1863/4885
US-20040242572-A1 New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture MCHR2, MCHR1, NPY1R CA1 4351/4885CA2 952/4885CA12 3074/4885
US-20080146554-A1 Substituted Cycloalkyl Derivatives, Process for the Manufacture thereof and Use thereof as Medicament CHRM1, CHRM2, CHRM3 CA1 4458/4885CA2 3223/4885CA12 3500/4885
US-20040152742-A1 Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds MCHR2, MCHR1, NPY1R CA1 4048/4885CA2 1732/4885CA12 3083/4885
US-20050261286-A1 Substituted cycloalkyl derivatives, process for the manufacture thereof and use thereof as medicament CHRM1, CHRM2, CHRM3 CA1 4458/4885CA2 3223/4885CA12 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.