Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968952 | 0.91 | PTGDR2 (0.43) | SLC6A4TBXA2RPTGDR2NPSR1SCN9A | |
| SCHEMBL3969463 | 0.84 | PTGDR2 (0.47) | PTGS2PTGDR2MEN1KMT2AMAPT | |
| SCHEMBL3962084 | 0.81 | PTGDR2 (0.39) | PTGS1PTGS2PTGDR2NPSR1MEN1 | |
| SCHEMBL3968970 | 0.80 | PTGDR2 (0.46) | PTGS2PTGDR2NPSR1MEN1KMT2A | |
| SCHEMBL3962109 | 0.79 | PTGDR2 (0.39) | PTGS2PTGDR2NPSR1MEN1KMT2A | |
| SCHEMBL3968018 | 0.79 | PTGDR2 (0.39) | PTGS2PTGDR2NPSR1MEN1KMT2A | |
| SCHEMBL3965620 | 0.79 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL3969315 | 0.79 | P2RX3 (0.36) | PTGDR2MEN1KMT2AL3MBTL1PGR | |
| SCHEMBL3967733 | 0.77 | PTGDR2 (0.40) | PTGS2PTGDR2NPSR1MEN1KMT2A | |
| SCHEMBL3968252 | 0.77 | PTGDR2 (0.38) | PTGS1PTGS2PTGDR2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |