Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12396077 | 1.00 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12396078 | 1.00 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL18938559 | 0.98 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL18784855 | 0.94 | TSHR (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL35612 | 0.91 | TSHR (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15081566 | 0.90 | THRB (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL395578 | 0.89 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367486 | 0.88 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2138102 | 0.88 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14278963 | 0.88 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255199-B2 | Hydrophilic silicone monomers, process for their preparation and thin films containing the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-02-09 | — | — | US | disclosed |
| US-20140163135-A1 | HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2014-06-12 | — | — | US | disclosed |
| US-20140163135-A1 | HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2014-06-12 | — | — | US | disclosed |
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110181833-A1 | HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-07-28 | — | — | US | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110181833-A1 | HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME | SMCHD1, MMS19, RAD51 | THRB 1220/4885TSHR 2405/4885ALDH1A1 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.