SCHEMBL393526

SCHEMBL393526

C=C(C)C(=O)OC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 2/20 0.39
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396935 0.83 THRB (0.42) TSHRALDH1A1THRB
SCHEMBL35615 0.81 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL396764 0.80 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL29011426 0.80 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL580729 0.77 THRB (0.50) TSHRALDH1A1THRB
SCHEMBL3915024 0.77 TSHR (0.48) TSHRALDH1A1THRB
SCHEMBL396294 0.77 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL397012 0.76 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL537010 0.75 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL4883024 0.74 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
US-20250368802-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY CANON KK (JP) 2025-12-04 US claimed
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-07-15 US claimed
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-04-03 US claimed
US-20240199816-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-20 US claimed
WO-2024123531-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-13 WO claimed
WO-2023153586-A1 NOVEL META-POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (META-POSS) COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION COMPRISING META-POSS COMPOUND PRODUCED THEREBY 주식회사 파이오셀 2023-08-17 WO claimed
CN-110235262-B Composition for organic electronic device sealant and sealant formed using the same 莫门蒂夫性能材料韩国株式会社 2023-07-18 CN claimed
EP-1945231-B1 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL PARTNERS LLP (US) 2021-11-10 EP claimed
US-10553824-B2 Encapsulation composition for organic electronic device, and encapsulation formed using same MOMENTIVE PERFORMANCE MATERIALS KOREA CO., LTD. (KR) 2020-02-04 US claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
WO-2012109228-A1 LOW-TACK, HYDROPHOBIC OPHTHALMIC DEVICE MATERIALS NOVARTIS AG (CH) 2012-08-16 WO claimed
US-20120202916-A1 Low-Tack, Hydrophobic Ophthalmic Device Materials NOVARTIS AG (CH) 2012-08-09 US claimed
US-8197803-B2 Method of forming a conformable solvent-based bandage and coating material ROCHAL INDUSTRIES, LLP (US) 2012-06-12 US claimed
US-20120114729-A1 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2012-05-10 US claimed
US-8142970-B2 Toner compositions XEROX CORPORATION (US) 2012-03-27 US claimed
WO-2010121024-A2 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2010-10-21 WO claimed
US-20090210002-A1 METHOD OF FORMING A CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES LLP (US) 2009-08-20 US claimed
US-20070041935-A1 Polymerizable cyanoacrylate monomer and volatile liquid selected from linear and cyclic siloxanes, polydimethylsiloxanes, isooctane, and octane; kits ROCHAL PARTNERS LLP 2007-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, OSTC TSHR 3556/4885ALDH1A1 4639/4885THRB 3131/4885
US-12600820-B2 Photocurable composition with high silicon content BIRC2, ACP1, IRS1 TSHR 4173/4885ALDH1A1 3351/4885THRB 4666/4885
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, SOST TSHR 3789/4885ALDH1A1 4652/4885THRB 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.