Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963734 | 0.92 | DRD2 (0.45) | KCNH2HRH3KDM4EPIK3CA | |
| SCHEMBL3964828 | 0.92 | KCNH2 (0.43) | KCNH2HRH3ALDH1A1MAPTKDM4E | |
| SCHEMBL3966727 | 0.90 | PIK3CD (0.40) | KCNH2HRH3KDM4ENPSR1PIK3CA | |
| SCHEMBL4198373 | 0.90 | KCNH2 (0.39) | KCNH2HRH3 | |
| SCHEMBL3970649 | 0.89 | KCNH2 (0.41) | KCNH2HRH3ESR1 | |
| SCHEMBL3962203 | 0.86 | ELOVL1 (0.39) | KCNH2HRH3MAPTLMNASMO | |
| SCHEMBL3970363 | 0.86 | DHFR (0.38) | KCNH2HRH3MAPTPIK3CASMO | |
| SCHEMBL3970650 | 0.85 | ELOVL1 (0.36) | KCNH2HRH3MAPTSMO | |
| SCHEMBL3970359 | 0.84 | ELOVL1 (0.46) | KCNH2HRH3MAPTKDM4ELMNA | |
| SCHEMBL3962208 | 0.84 | HTR2A (0.47) | HRH3ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041904-A1 | QUINOLINE COMPOUNDS HAVING AN ACTIVITY AGAINST THE GABAB RECEPTOR | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | WO | claimed |
| WO-2009041904-A1 | QUINOLINE COMPOUNDS HAVING AN ACTIVITY AGAINST THE GABAB RECEPTOR | ASTRAZENECA AB (SE) | 2009-04-02 | — | — | WO | disclosed |