Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970236 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KDM4AITGA4ITGB7KMT2A | |
| SCHEMBL14921097 | 0.92 | ALDH1A1 (0.66) | ALDH1A1KDM4AITGA4ITGB7KMT2A | |
| SCHEMBL20515138 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4AITGA4ITGB7KMT2A | |
| SCHEMBL20515136 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4AITGA4ITGB7KMT2A | |
| SCHEMBL7518908 | 0.87 | ITGA4 (0.54) | ALDH1A1KDM4AITGA4ITGB7PDCD1 | |
| SCHEMBL7518902 | 0.87 | ITGA4 (0.54) | ALDH1A1KDM4AITGA4ITGB7PDCD1 | |
| SCHEMBL6616257 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4AITGA4ITGB7 | |
| SCHEMBL6616256 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4AITGA4ITGB7 | |
| SCHEMBL756835 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4AKMT2AKDM4EPDCD1 | |
| SCHEMBL756836 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4AKMT2AKDM4EPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658394-B2 | Methods, cells and systems for incorporating non-canonical amino acids into proteins | WATERSTONE PHARMACEUTICALS (CN) | 2014-02-25 | — | — | US | claimed |
| US-20120237971-A1 | METHODS, CELLS AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-09-20 | — | — | US | claimed |
| WO-2012092629-A2 | METHODS, CELLS, AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-07-05 | — | — | WO | claimed |
| EP-4720264-A1 | AMINOACYL-TRNA SYNTHETASE SETS | United Kingdom Research and Innovation (GB) | 2026-04-08 | — | — | EP | disclosed |
| US-20250346939-A1 | Method of Making Proteins with Non-Standard Amino Acids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250320452-A1 | MICROORGANISMS AND USES THEREOF | RES & INNOVATION UK (GB) | 2025-10-16 | — | — | US | disclosed |
| US-20250279156-A1 | METHODS FOR OPTIMISING PROTEIN PRODUCTION | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-09-04 | — | — | US | disclosed |
| US-12385035-B2 | Synthetic genome | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-08-12 | — | — | US | disclosed |
| US-20250206782-A1 | BIOLOGICAL POLYMERS | RES & INNOVATION UK (GB) | 2025-06-26 | — | — | US | disclosed |
| WO-2024246123-A1 | AMINOACYL-tRNA SYNTHETASE SETS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2024-12-05 | — | — | WO | disclosed |
| US-20240229013-A9 | SYNTHETIC GENOME | SCARAB GENOMICS, LLC | 2024-07-11 | — | — | US | disclosed |
| US-9834775-B2 | Recombinant cells and organisms having persistent nonstandard amino acid dependence and methods of making them | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-12-05 | — | — | US | disclosed |
| US-20160230176-A1 | Recombinant Cells and Organisms Having Persistent Nonstandard Amino Acid Dependence and Methods of Making Them | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | disclosed |
| WO-2015048364-A1 | RECOMBINANT CELLS AND ORGANISMS HAVING PERSISTENT NONSTANDARD AMINO ACID DEPENDENCE AND METHODS OF MAKING THEM | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-02 | — | — | WO | disclosed |
| US-8658394-B2 | Methods, cells and systems for incorporating non-canonical amino acids into proteins | WATERSTONE PHARMACEUTICALS (CN) | 2014-02-25 | — | — | US | disclosed |
| CN-102827827-A | Orthogonal translation components for in vivo incorporation of unnatural amino acids | SCRIPPS RESEARCH INST | 2012-12-19 | — | — | CN | disclosed |
| US-20120237971-A1 | METHODS, CELLS AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-09-20 | — | — | US | disclosed |
| WO-2012092629-A2 | METHODS, CELLS, AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-07-05 | — | — | WO | disclosed |
| WO-2009049223-A2 | METHODS AND COMPOSITIONS FOR THE SITE-SELECTIVE INCORPORATION OF FLUORINATED AMINO ACIDS INTO POLYPEPTIDES | IRM LLC (BM) | 2009-04-16 | — | — | WO | disclosed |
| CN-101048506-A | Orthogonal translation Components for in vivo incorporation of unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2007-10-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206782-A1 | BIOLOGICAL POLYMERS | NSUN3, AARS1, TARBP1 | ALDH1A1 4335/4885KDM4A 3685/4885ITGA4 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.