Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883894 | 0.88 | LTA4H (0.44) | LTA4HRAB9AMAPTMEN1GFER | |
| SCHEMBL3970202 | 0.85 | RAB9A (0.47) | SMN1; SMN2RAB9ANPC1PANK3MAPT | |
| SCHEMBL3971172 | 0.79 | PTAFR (0.48) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL13883784 | 0.75 | MAPK8 (0.43) | MAPTALDH1A1LMNA | |
| SCHEMBL3975570 | 0.74 | RAB9A (0.47) | RAB9AMAPTMEN1GFERKMT2A | |
| SCHEMBL3972961 | 0.72 | RAB9A (0.45) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL13578029 | 0.71 | CPT2 (0.50) | LTA4HMAPTMEN1GFERKMT2A | |
| SCHEMBL3976475 | 0.71 | PTAFR (0.45) | SMN1; SMN2RAB9ANPC1MAPTKMT2A | |
| SCHEMBL13883788 | 0.69 | PTAFR (0.40) | SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL13883746 | 0.68 | MTNR1A (0.52) | SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | claimed |