Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478290 | 0.86 | HSD11B1 (0.38) | HSD11B1CES2CES1BCHEMPL | |
| SCHEMBL448487 | 0.80 | HSD11B1 (0.47) | HSD11B1CES2CES1BCHEMPL | |
| SCHEMBL29551965 | 0.80 | HSD11B1 (0.47) | HSD11B1CES2CES1BCHEMPL | |
| SCHEMBL2525080 | 0.80 | KCNN4 (0.44) | HSD11B1KCNN4IDO1ALDH1A1POLB | |
| SCHEMBL23886265 | 0.79 | HSD11B1 (0.37) | HSD11B1CES2CES1BCHEMPL | |
| SCHEMBL30018006 | 0.79 | HSD11B1 (0.37) | HSD11B1CES2CES1BCHEMPL | |
| SCHEMBL8863496 | 0.79 | MPL (0.35) | HSD11B1CES2CES1MPLKCNN4 | |
| SCHEMBL6936394 | 0.78 | CES2 (0.34) | CES2CES1MPLKIF11 | |
| SCHEMBL4002333 | 0.78 | HSD11B1 (0.39) | HSD11B1CES2CES1BCHEMPL | |
| Hydrochloric Acid SCHEMBL29168009 | 0.77 | HTR2C (0.37) | HSD11B1CES2CES1BCHEMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12337036-B2 | Compounds and methods for trans-membrane delivery of molecules | APOSENSE LTD (IL) | 2025-06-24 | — | — | US | claimed |
| CN-115867091-A | Perovskite solar cell and preparation method thereof | 宣城先进光伏技术有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-2037951-A2 | METHODS AND COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS VIA MODULATION OF MEGALIN ACTIVITY | Sirion Therapeutics, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007150046-A2 | METHODS AND COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS VIA MODULATION OF MEGALIN ACTIVITY | SIRION THERAPEUTICS, INC (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12337036-B2 | Compounds and methods for trans-membrane delivery of molecules | LDLR, NPC1L1, ABCB4 | HSD11B1 2240/4885CES2 516/4885CES1 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.