Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448487 | 0.82 | HSD11B1 (0.47) | HSD11B1CES2CES1BCHESLC22A12 | |
| SCHEMBL29551965 | 0.82 | HSD11B1 (0.47) | HSD11B1CES2CES1BCHESLC22A12 | |
| SCHEMBL1600455 | 0.79 | KCNN4 (0.41) | HSD11B1CES2CES1SLC22A12KCNN4 | |
| SCHEMBL30757407 | 0.79 | KCNN4 (0.41) | HSD11B1CES2CES1SLC22A12KCNN4 | |
| SCHEMBL3972408 | 0.78 | HSD11B1 (0.38) | HSD11B1CES2CES1BCHEBACE1 | |
| SCHEMBL1201504 | 0.78 | CES2 (0.41) | HSD11B1CES2CES1BCHEBACE1 | |
| SCHEMBL10779525 | 0.78 | HSD11B1 (0.38) | HSD11B1CES2CES1BCHEBACE1 | |
| SCHEMBL2968190 | 0.78 | HSD11B1 (0.38) | HSD11B1CES2CES1BCHEBACE1 | |
| SCHEMBL2965656 | 0.78 | CES2 (0.41) | HSD11B1CES2CES1BCHEBACE1 | |
| SCHEMBL28478290 | 0.78 | HSD11B1 (0.38) | HSD11B1CES2CES1BCHEKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195799-A | Pyrazine derivative and application thereof in inhibition of SHP2 | 勤浩医药（苏州）有限公司 | 2022-03-18 | — | — | CN | disclosed |
| EP-1883619-B1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORP (KR) | 2013-03-20 | — | — | EP | disclosed |
| US-7495126-B2 | Process of preparation of substituted tetrafluorobenzylaniline compound and its pharmaceutically approved salts | CHOONGWAE PHARMA CORPORATION (KR) | 2009-02-24 | — | — | US | disclosed |
| US-20080167492-A1 | Process of Preparation of Substituted Tetrafluorobenzylaniline Compound and Its Pharmaceutically Approved Salts | CHOONGWAE PHARMA CORPORATION (KR) | 2008-07-10 | — | — | US | disclosed |
| EP-1883619-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | Choongwae Pharma Corporation (KR) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126846-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORPORATION (KR) | 2006-11-30 | — | — | WO | disclosed |
| US-20050192359-A1 | N-biphenylamides and fungicidal compositions containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-01 | — | — | US | disclosed |
| EP-1486483-A1 | N-BIPHENYLAMIDES AND FUNGICIDAL COMPOSITIONS CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192359-A1 | N-biphenylamides and fungicidal compositions containing the same | CBR3, ARNT, CBR1 | HSD11B1 2461/4885CES2 1280/4885CES1 1297/4885 |
| US-20080167492-A1 | Process of Preparation of Substituted Tetrafluorobenzylaniline Compound and Its Pharmaceutically Approved Salts | IL5, CYP3A5, PGA5 | HSD11B1 1755/4885CES2 3381/4885CES1 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.