Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375795 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1TSHRHTT | |
| SCHEMBL21439085 | 0.71 | CCR2 (0.41) | CCR2SLC6A2LMNAHPGDALDH1A1 | |
| SCHEMBL21447477 | 0.71 | CCR2 (0.41) | CCR2SLC6A2LMNAHPGDALDH1A1 | |
| SCHEMBL23435289 | 0.71 | CCR2 (0.41) | CCR2SLC6A2LMNAHPGDALDH1A1 | |
| SCHEMBL21447376 | 0.71 | CCR2 (0.41) | CCR2SLC6A2LMNAHPGDALDH1A1 | |
| SCHEMBL23356985 | 0.68 | LMNA (0.49) | CCR2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL23375803 | 0.68 | LMNA (0.49) | CCR2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL21438851 | 0.68 | LMNA (0.49) | CCR2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL23375795 | 0.68 | LMNA (0.49) | CCR2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL23375794 | 0.68 | LMNA (0.49) | CCR2LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | disclosed |
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | GPR119, SLC2A4, SLC2A1 | CCR2 1081/4885SLC6A2 2549/4885ATM 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.