Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972482 | 0.83 | CCR2 (0.38) | ALDH1A1HTTTSHRMEN1KMT2A | |
| SCHEMBL29688113 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL21439250 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL29688152 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL23375509 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL6081939 | 0.77 | LMNA (0.51) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL15978552 | 0.76 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL15978556 | 0.76 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL15977390 | 0.76 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1HTTTSHRMEN1 | |
| SCHEMBL15977383 | 0.76 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1HTTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764888-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| CN-101142167-A | Compounds that stimulate glucose utilization and methods of use | UNIV ALBERTA (CA) | 2008-03-12 | — | — | CN | claimed |
| EP-1868982-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | The Governors of the University of Alberta (CA) | 2007-12-26 | — | — | EP | claimed |
| WO-2006117686-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-11-09 | — | — | WO | claimed |
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2005-08-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | GPR119, SLC2A4, SLC2A1 | ALDH1A1 1918/4885L3MBTL1 4705/4885HTT 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.