Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PYGM | P11217 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970918 | 0.87 | ALDH1A1 (0.49) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL24695865 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL2035541 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL10380346 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL21277516 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| Phosphoric Acid SCHEMBL3691397 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL17135514 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL3085565 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1POLBKMT2ASMN1; SMN2PYGM | |
| SCHEMBL3090864 | 0.77 | TK1 (0.55) | SMN1; SMN2TK1BLMPMP22CYP1A2 | |
| SCHEMBL19389398 | 0.76 | TK1 (0.52) | ALDH1A1POLBKMT2ASMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054406-A1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | RESprotect GmbH (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008017515-A1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | RESPROTECT GMBH (DE) | 2008-02-14 | — | — | WO | disclosed |