SCHEMBL2035541

SCHEMBL2035541

O=c1[nH]c(=O)n([C@H]2CC[C@@H](CO)O2)cc1Br

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
POLB P06746 1/20 0.56
KMT2A Q03164 1/20 0.56
PYGM P11217 1/20 0.53
LMNA P02545 4/20 0.47
ALB P02768 2/20 0.47
MAPK1 P28482 1/20 0.47
TK1 P04183 4/20 0.44
TSHR P16473 2/20 0.43
PKM P14618 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10380346 1.00 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2POLBKMT2APYGM
SCHEMBL24695865 1.00 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2POLBKMT2APYGM
Phosphoric Acid SCHEMBL3691397 0.95 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2POLBKMT2APYGM
SCHEMBL21277516 0.90 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2POLBKMT2APYGM
SCHEMBL23485 0.85 LMNA (0.58) ALDH1A1POLBLMNAALBTK1
SCHEMBL22992337 0.85 LMNA (0.58) ALDH1A1POLBLMNAALBTK1
SCHEMBL14596607 0.85 LMNA (0.58) ALDH1A1POLBLMNAALBTK1
SCHEMBL19657129 0.85 LMNA (0.48) ALDH1A1SMN1; SMN2POLBLMNAALB
SCHEMBL762579 0.85 LMNA (0.58) ALDH1A1POLBLMNAALBTK1
SCHEMBL925743 0.85 LMNA (0.58) ALDH1A1POLBLMNAALBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580609-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2025-07-09 EP disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 CN disclosed
WO-2024050372-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2024-03-07 WO disclosed
US-20230293526-A1 METHOD FOR TREATING CANCER WITH A REVERSE TRANSCRIPTASE INHIBITOR PRIMEFOUR THERAPEUTICS, INC. 2023-09-21 US disclosed
CN-116064869-A Diagnosis of drug-resistant Mycobacterium tuberculosis using mass spectrometry 贝克顿迪金森公司 2023-05-05 CN disclosed
WO-2022256625-A1 LINE-1 INHIBITORS AS COGNITIVE ENHANCERS TRANSPOSON THERAPEUTICS, INC. (US) 2022-12-08 WO disclosed
CN-101564571-B Medical apparatus containing rapamycin analogue 艾博特公司 2017-02-22 CN disclosed
US-9394565-B2 Allele-specific sequence variation analysis AGENA BIOSCIENCE, INC. (US) 2016-07-19 US disclosed
US-8871687-B2 Nucleic acid sequencing by single-base primer extension QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) 2014-10-28 US disclosed
CN-101637624-B Medical devices containing rapamycin analogs ABBOTT LABORATORIES (US) 2014-10-15 CN disclosed
WO-2005033328-A2 COMPOSITIONS AND PROCESSES FOR GENOTYPING SINGLE NUCLEOTIDE POLYMORPHISMS PERKINELMER LAS, INC. (US) 2005-04-14 WO disclosed
WO-2005024068-A2 ALLELE-SPECIFIC SEQUENCE VARIATION ANALYSIS SEQUENOM, INC. (US) 2005-03-17 WO disclosed
US-20050009053-A1 Fragmentation-based methods and systems for de novo sequencing SEQUENOM, INC. 2005-01-13 US disclosed
WO-2004097369-A2 FRAGMENTATION-BASED METHODS AND SYSTEMS FOR DE NOVO SEQUENCING SEQUENOM, INC. (US) 2004-11-11 WO disclosed
WO-2004050839-A2 FRAGMENTATION-BASED METHODS AND SYSTEMS FOR SEQUENCE VARIATION DETECTION AND DISCOVERY SEQUENOM, INC. (US) 2004-06-17 WO disclosed
US-20040077004-A1 Use of nucleotide analogs in the analysis of oligonucleotide mixtures and highly multiplexed nucleic acid sequencing TRUSTEES OF BOSTON UNIVERSITY, THE 2004-04-22 US disclosed
EP-1373561-A2 USE OF NUCLEOTIDE ANALOGS IN THE ANALYSIS OF OLIGONUCLEOTIDE MIXTURES AND IN HIGHLY MULTIPLEXED NUCLEIC ACID SEQUENCING The Trustees of Boston University (US) 2004-01-02 EP disclosed
US-6660229-B2 Synthesizing extension products of the target nucleic acid in the presence of chain terminating nucleotides and mass-matched nucleotides; determining the mass of each extension product; and calculating a mass shift THE TRUSTEES OF BOSTON UNIVERSITY 2003-12-09 US disclosed
US-20020045178-A1 Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing THE TRUSTEES OF BOSTON UNIVERSITY 2002-04-18 US disclosed
WO-2001096607-A2 USE OF NUCLEOTIDE ANALOGS IN THE ANALYSIS OF OLIGONUCLEOTIDE MIXTURES AND IN HIGHLY MULTIPLEXED NUCLEIC ACID SEQUENCING THE TRUSTEES OF BOSTON UNIVERSITY (US) 2001-12-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293526-A1 METHOD FOR TREATING CANCER WITH A REVERSE TRANSCRIPTASE INHIBITOR TYMP, TYMS, DCTD ALDH1A1 833/4885SMN1; SMN2 3957/4885POLB 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.