Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380346 | 0.90 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1POLBKMT2APYGM | |
| SCHEMBL24695865 | 0.90 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1POLBKMT2APYGM | |
| SCHEMBL2035541 | 0.90 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1POLBKMT2APYGM | |
| SCHEMBL24371230 | 0.86 | TK1 (0.56) | ALDH1A1POLBTK1LMNATSHR | |
| Phosphoric Acid SCHEMBL3691397 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1POLBKMT2APYGM | |
| SCHEMBL21277455 | 0.81 | TK1 (0.42) | TK1LMNATSHRALBPKM | |
| SCHEMBL21277407 | 0.81 | TK1 (0.42) | TK1LMNATSHRALBPKM | |
| SCHEMBL21277491 | 0.81 | LMNA (0.58) | SMN1; SMN2TK1LMNATSHRALB | |
| SCHEMBL21277425 | 0.81 | TK1 (0.42) | TK1LMNATSHRALBPKM | |
| SCHEMBL3972864 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1POLBKMT2APYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931319-B1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNATX INC (US) | 2019-08-21 | — | — | EP | disclosed |