Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PYGM | P11217 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035541 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBKMT2APYGM | |
| SCHEMBL24695865 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBKMT2APYGM | |
| Phosphoric Acid SCHEMBL3691397 | 0.95 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBKMT2APYGM | |
| SCHEMBL21277516 | 0.90 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2POLBKMT2APYGM | |
| SCHEMBL23485 | 0.85 | LMNA (0.58) | ALDH1A1POLBLMNAALBTK1 | |
| SCHEMBL22992337 | 0.85 | LMNA (0.58) | ALDH1A1POLBLMNAALBTK1 | |
| SCHEMBL14596607 | 0.85 | LMNA (0.58) | ALDH1A1POLBLMNAALBTK1 | |
| SCHEMBL19657129 | 0.85 | LMNA (0.48) | ALDH1A1SMN1; SMN2POLBLMNAALB | |
| SCHEMBL762579 | 0.85 | LMNA (0.58) | ALDH1A1POLBLMNAALBTK1 | |
| SCHEMBL925743 | 0.85 | LMNA (0.58) | ALDH1A1POLBLMNAALBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968788-A | DRUG DELIVERY, ANTITUMOR AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-11-06 | — | — | US | claimed |
| WO-1990008155-A1 | BIOLOGICALLY REVERSIBLE PHOSPHATE AND PHOSPHONATE PROTECTIVE GROUPS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-07-26 | — | — | WO | disclosed |