Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967394 | 0.85 | PLA2G4A (0.46) | PLA2G4ARORCMTNR1AMTNR1BMETTL3 | |
| SCHEMBL3971169 | 0.84 | PLA2G4A (0.45) | PLA2G4ARORCMTNR1AMTNR1B | |
| SCHEMBL3972371 | 0.83 | SMN1; SMN2 (0.45) | PLA2G4AALDH1A1NPC1USP2 | |
| SCHEMBL3972961 | 0.83 | RAB9A (0.45) | PLA2G4ARORCMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3971114 | 0.83 | HIF1A (0.45) | PLA2G4ARORCMTNR1AMTNR1BMETTL3 | |
| SCHEMBL3976087 | 0.78 | NPC1 (0.49) | PLA2G4AMITFKLF5RORCMTNR1A | |
| SCHEMBL3974621 | 0.76 | MAPK8 (0.46) | PLA2G4AMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL4330821 | 0.76 | CPT2 (0.48) | CYSLTR2CYSLTR1MITFKLF5NAMPT | |
| SCHEMBL3970202 | 0.72 | RAB9A (0.47) | PLA2G4AALDH1A1HPGDNPC1 | |
| SCHEMBL3972129 | 0.72 | PLA2G4A (0.53) | PLA2G4AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |