Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 7/20 | 0.50 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883891 | 0.89 | HTR6 (0.49) | HTR7TNFSF11TNFFGFR1NR4A2 | |
| SCHEMBL3967405 | 0.80 | MTNR1A (0.55) | FGFR1NR4A2MTNR1AMTNR1BPLA2G4A | |
| SCHEMBL3970720 | 0.79 | PLA2G4A (0.61) | MTNR1AMTNR1BPLA2G4A | |
| SCHEMBL3969149 | 0.79 | MTNR1A (0.54) | FGFR1NR4A2MTNR1AMTNR1BPLA2G4A | |
| Hydrochloric Acid SCHEMBL3969364 | 0.78 | MTNR1A (0.53) | FGFR1NR4A2MTNR1AMTNR1BPLA2G4A | |
| SCHEMBL3970192 | 0.78 | MTNR1A (0.51) | ALDH1A1FGFR1NR4A2MTNR1AMTNR1B | |
| SCHEMBL13883856 | 0.78 | MTNR1A (0.53) | FGFR1NR4A2MTNR1AMTNR1BPLA2G4A | |
| SCHEMBL3972972 | 0.77 | MTNR1A (0.52) | FGFR1NR4A2MTNR1AMTNR1BPLA2G4A | |
| SCHEMBL3972129 | 0.76 | PLA2G4A (0.53) | FGFR1NR4A2MTNR1AMTNR1BPLA2G4A | |
| SCHEMBL7388920 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |