Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL395658 | 0.80 | TSHR (0.33) | — | |
| Hydrochloric Acid SCHEMBL11026182 | 0.80 | SMN1; SMN2 (0.37) | — | |
| Hydrochloric Acid SCHEMBL394711 | 0.79 | CA2 (0.32) | — | |
| Fluoride Ion SCHEMBL6304345 | 0.76 | CA2 (0.32) | — | |
| Bromide SCHEMBL6312692 | 0.76 | CA2 (0.32) | — | |
| Iodide SCHEMBL6307196 | 0.76 | CA2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL395656 | 0.75 | CA4 (0.37) | — | |
| Hydrochloric Acid SCHEMBL715516 | 0.73 | TRPA1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL28544998 | 0.71 | MEN1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL3154711 | 0.71 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431659-B2 | Prepolymerized catalyst for olefin polymerization, method of producing this prepolymerized catalyst and method of producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20120095173-A1 | PREPOLYMERIZED CATALYST FOR OLEFIN POLYMERIZATION, METHOD OF PRODUCING THIS PREPOLYMERIZED CATALYST AND METHOD OF PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-19 | — | — | US | disclosed |
| US-8101537-B2 | Prepolymerized catalyst for olefin polymerization, method of producing this prepolymerized catalyst and method of producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20100280196-A1 | PREPOLYMERIZED CATALYST FOR OLEFIN POLYMERIZATION, METHOD OF PRODUCING THIS PREPOLYMERIZED CATALYST AND METHOD OF PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-04 | — | — | US | disclosed |