Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 18/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969848 | 0.96 | PLA2G4A (0.52) | PLA2G4AMTNR1AMTNR1BALDH1A1L3MBTL1 | |
| SCHEMBL3970351 | 0.92 | MTNR1A (0.51) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL13884101 | 0.88 | MTNR1A (0.50) | PLA2G4AMTNR1AMTNR1BALDH1A1L3MBTL1 | |
| SCHEMBL3970925 | 0.85 | MTNR1A (0.55) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3976494 | 0.82 | NPC1 (0.52) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL3975570 | 0.80 | RAB9A (0.47) | PLA2G4AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3968509 | 0.79 | MTNR1A (0.45) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL13883771 | 0.79 | MTNR1A (0.56) | PLA2G4AMTNR1AMTNR1B | |
| SCHEMBL13883686 | 0.79 | RORC (0.45) | MTNR1AMTNR1B | |
| SCHEMBL13883906 | 0.76 | TMEM97 (0.45) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |