SCHEMBL3977574

SCHEMBL3977574

CCc1cc(C2(c3cc(CC)c(O)c(CC)c3)C3CC4CC(C3)CC2C4)cc(CC)c1O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
HSD11B1 P28845 12/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CTSD P07339 1/20 0.33
BACE1 P56817 1/20 0.33
BACE2 Q9Y5Z0 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOA P21397 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4583324 0.89 CTSD (0.34) CYP1A2CYP3A4CYP2C9HSD11B1CTSD
SCHEMBL10051861 0.84 HSD11B1 (0.33) HSD11B1MEN1KMT2A
SCHEMBL3975221 0.82 ESR1 (0.40) HSD11B1CTSDBACE1BACE2MEN1
SCHEMBL3981800 0.77 CASP1 (0.34) CYP1A2CYP3A4HSD11B1MEN1KMT2A
SCHEMBL2047938 0.77 ACHE (0.44) CYP2C9HSD11B1MEN1KMT2A
SCHEMBL3973937 0.75 ESR1 (0.40) MEN1KMT2AALDH1A1
SCHEMBL3978480 0.74 PTPN1 (0.40) CYP1A2CYP3A4CYP2C9HSD11B1MEN1
SCHEMBL3983497 0.73 ALOX5 (0.39) HSD11B1GABRA1GABRB2MEN1KMT2A
SCHEMBL3973784 0.73 HSD17B10 (0.38) CYP1A2CYP3A4CYP2C9HSD11B1MEN1
SCHEMBL3976244 0.73 HSD11B1 (0.38) HSD11B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed