Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL397542

CC(=O)C1=CCCC2CCC1N2.O=C(O)C(F)(F)F

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 6/20 0.80
CHRNA4 P43681 4/20 0.80
CHRNA7 P36544 3/20 0.80
ALDH1A1 P00352 1/20 0.80
CHRNA3 P32297 4/20 0.33
CHRNA1 P02708 1/20 0.33
CHRNB4 P30926 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13589890 0.89 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
SCHEMBL160708 0.89 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
SCHEMBL21307962 0.89 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
Trifluoroacetic Acid SCHEMBL16431875 0.85 CHRNB2 (0.57) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
SCHEMBL21308152 0.73 CHRNB2 (0.70) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
SCHEMBL12102742 0.73 CHRNB2 (0.69) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
Trifluoroacetic Acid SCHEMBL3902122 0.69 ALDH1A1 (0.38) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
SCHEMBL23613217 0.65 CHRNB2 (0.48) CHRNB2CHRNA4CHRNA7ALDH1A1CHRNA3
Trifluoroacetic Acid SCHEMBL21598176 0.64 KDM1A (0.33) CHRNB2CHRNA4CHRNA7CHRNA3
Trifluoroacetic Acid SCHEMBL939167 0.63 ARG1 (0.34) CHRNB2CHRNA4CHRNA7CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114544835-B Preparation and quantitative analysis method of high-purity cyanobacteria polypeptide metabolite 舟山市食品药品检验检测研究院 2024-07-09 CN claimed
CN-114544835-A Preparation and quantitative analysis method of high-purity blue algae polypeptide metabolite 舟山市食品药品检验检测研究院 2022-05-27 CN claimed
US-7428045-B2 Raman spectral analysis of pathogens CHEMIMAGE CORPORATION (US) 2008-09-23 US claimed
EP-1915597-A2 RAMAN SPECTRAL ANALYSIS OF PATHOGENS Chemimage Corporation (US) 2008-04-30 EP claimed
WO-2007021485-A2 RAMAN SPECTRAL ANALYSIS OF PATHOGENS CHEMIMAGE CORPORATION (US) 2007-02-22 WO claimed
US-20060055923-A1 Raman spectral analysis of pathogens CHEMIMAGE CORPORATION 2006-03-16 US claimed
CN-114544835-B Preparation and quantitative analysis method of high-purity cyanobacteria polypeptide metabolite 舟山市食品药品检验检测研究院 2024-07-09 CN disclosed
EP-4051247-B1 TRANSDERMAL PATCH UNIV OF SUNDERLAND (GB) 2023-11-01 EP disclosed
US-20230173090-A1 COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-06-08 US disclosed
WO-2023097186-A1 COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-01 WO disclosed
EP-4172187-A1 COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY The Regents of the University of California (US) 2023-05-03 EP disclosed
EP-4158002-A1 COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION The Regents of the University of California (US) 2023-04-05 EP disclosed
US-20220387342-A1 TRANSDERMAL PATCH UNIVERSITY OF SUNDERLAND (GB) 2022-12-08 US disclosed
WO-1999051764-A1 METHOD FOR DETECTION OF BACILLUS CEREUS EMETIC TOXIN AND A KIT THEREFOR LOCUS GENEX OY (FI) 1999-10-14 WO disclosed
EP-0760681-B1 MODIFICATION OF CLOSTRIDIAL TOXINS FOR USE AS TRANSPORT PROTEINS ALLERGAN INC (US) 1999-09-01 EP disclosed
US-5821249-A Anhydroecogonine compounds and their use as anticholinergic agents UNIVERSITY OF ROCHESTER (US) 1998-10-13 US disclosed
EP-0760681-A1 MODIFICATION OF CLOSTRIDIAL TOXINS FOR USE AS TRANSPORT PROTEINS ALLERGAN, INC (US) 1997-03-12 EP disclosed
US-5552407-A Anhydroecgonine compounds and their use as anticholinergic agents NEW YORK UNIVERSITY MEDICAL CENTER (US) 1996-09-03 US disclosed
WO-1995032738-A1 MODIFICATION OF CLOSTRIDIAL TOXINS FOR USE AS TRANSPORT PROTEINS ALLERGAN, INC. (US) 1995-12-07 WO disclosed
WO-1994029306-A1 COCAINE DERIVATIVES AND THEIR USE AS ANTICHOLINERGIC AGENTS NEW YORK UNIVERSITY (US) 1994-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173090-A1 COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY PARK7, PRLHR, SNCA CHRNB2 4/4885CHRNA4 31/4885CHRNA7 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.