SCHEMBL3976244

SCHEMBL3976244

Oc1c(F)cc(C2(c3cc(F)c(O)c(F)c3)C3CC4CC(C3)CC2C4)cc1F

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 11/20 0.38
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
GFER P55789 1/20 0.31
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4583499 0.88 HSD11B1 (0.33) HSD11B1MEN1KMT2A
SCHEMBL3974982 0.80 MEN1 (0.42) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3976140 0.77 CYP3A4 (0.38) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3973784 0.77 HSD17B10 (0.38) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL2047938 0.77 ACHE (0.44) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3978480 0.74 PTPN1 (0.40) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL10051861 0.74 HSD11B1 (0.33) HSD11B1MEN1KMT2A
SCHEMBL3977574 0.73 CYP1A2 (0.36) HSD11B1MEN1KMT2A
SCHEMBL4583841 0.73 HSD11B1 (0.33) HSD11B1MEN1KMT2A
SCHEMBL3978462 0.72 KMT2A (0.41) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed