SCHEMBL3976140

SCHEMBL3976140

Oc1c(Br)cc(C2(c3cc(Br)c(O)c(Br)c3)C3CC4CC(C3)CC2C4)cc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD11B1 P28845 9/20 0.34
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TTR P02766 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
ALB P02768 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CASP1 P29466 1/20 0.32
RECQL P46063 1/20 0.32
HIF1A Q16665 1/20 0.32
AKR1C1 Q04828 1/20 0.32
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976577 0.80 MEN1 (0.42) HSD11B1MEN1KMT2AALOX15ALOX12
SCHEMBL2047938 0.77 ACHE (0.44) HSD11B1MEN1KMT2ACA1CA2
SCHEMBL3976244 0.77 HSD11B1 (0.38) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3973784 0.77 HSD17B10 (0.38) CYP3A4TSHRHSD11B1MEN1KMT2A
SCHEMBL3978480 0.74 PTPN1 (0.40) CYP3A4HSD11B1MEN1KMT2AHPGD
SCHEMBL10051861 0.74 HSD11B1 (0.33) HSD11B1MEN1KMT2A
SCHEMBL3977574 0.73 CYP1A2 (0.36) CYP3A4HSD11B1MEN1KMT2AALDH1A1
SCHEMBL3973285 0.72 MEN1 (0.41) CYP3A4TSHRTDP1MEN1KMT2A
SCHEMBL9805640 0.72 ALOX5AP (0.48) CYP3A4TSHRTDP1HSD11B1HSD17B10
SCHEMBL3981800 0.70 CASP1 (0.34) CYP3A4TSHRHSD11B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed