Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976440 | 0.87 | PRKCZ (0.59) | PRKCZMAPK1POLBALDH1A1LMNA | |
| SCHEMBL3979142 | 0.86 | ALDH1A1 (0.65) | PRKCZMAPK1POLBALDH1A1LMNA | |
| SCHEMBL3980970 | 0.84 | ALDH1A1 (0.65) | PRKCZMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL4963547 | 0.83 | PRKCZ (0.67) | PRKCZMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL3981694 | 0.81 | PRKCZ (0.62) | PRKCZMAPK1POLBALDH1A1LMNA | |
| SCHEMBL3974317 | 0.81 | PRKCZ (0.54) | PRKCZMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL3976107 | 0.81 | PRKCZ (0.58) | PRKCZMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL3976339 | 0.81 | PRKCZ (0.58) | PRKCZMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL3973230 | 0.77 | PRKCZ (0.60) | PRKCZMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL11518208 | 0.76 | PRKCZ (1.00) | PRKCZMAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |