Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979142 | 0.90 | ALDH1A1 (0.65) | MAPTALDH1A1MAPK1PRKCZHSD17B10 | |
| SCHEMBL3976440 | 0.86 | PRKCZ (0.59) | MAPTALDH1A1MAPK1PRKCZRAB9A | |
| SCHEMBL3975200 | 0.84 | PRKCZ (0.48) | MAPTALDH1A1MAPK1PRKCZRAB9A | |
| SCHEMBL3975696 | 0.81 | PRKCZ (0.45) | MAPTALDH1A1MAPK1PRKCZRAB9A | |
| SCHEMBL3980156 | 0.81 | PRKCZ (0.45) | MAPTALDH1A1CNR1PRKCZRAB9A | |
| SCHEMBL3972011 | 0.80 | PRKCZ (0.57) | MAPTALDH1A1MAPK1PRKCZRAB9A | |
| SCHEMBL3974360 | 0.79 | PRKCZ (0.62) | MAPTALDH1A1MAPK1PRKCZRAB9A | |
| SCHEMBL3972275 | 0.78 | RORB (0.49) | MAPTALDH1A1PRKCZHSD17B10LMNA | |
| SCHEMBL3979210 | 0.78 | MAPT (0.69) | MAPTALDH1A1MAPK1CNR1PRKCZ | |
| SCHEMBL3975112 | 0.77 | PRKCZ (0.50) | MAPTALDH1A1PRKCZHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |