Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589736 | 0.85 | CYP2D6 (0.32) | MTNR1AMTNR1B | |
| SCHEMBL589453 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL28044597 | 0.72 | USP2 (0.30) | — | |
| SCHEMBL591196 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL592164 | 0.68 | — | — | |
| SCHEMBL591061 | 0.63 | NOS1 (0.38) | — | |
| SCHEMBL12466363 | 0.62 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL591101 | 0.61 | MLYCD (0.36) | — | |
| SCHEMBL591483 | 0.61 | HTR1D (0.32) | — | |
| SCHEMBL3123962 | 0.59 | NPC1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120932-A1 | INDAZOLE DERIVATIVES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Nerviano Medical Sciences S.r.l. (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008074749-A9 | INDAZOLE DERIVATIVES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-05-07 | — | — | WO | disclosed |
| WO-2008074749-A1 | INDAZOLE DERIVATIVES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2008-06-26 | — | — | WO | disclosed |