Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589736 | 0.86 | CYP2D6 (0.32) | USP2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28044536 | 0.74 | HTR7 (0.33) | — | |
| SCHEMBL3977577 | 0.72 | MTNR1A (0.31) | — | |
| SCHEMBL28044545 | 0.66 | MAPT (0.35) | ALDH1A1 | |
| SCHEMBL589453 | 0.66 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL591196 | 0.64 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27725923 | 0.64 | PLK1 (0.35) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPK1 | |
| SCHEMBL7802304 | 0.64 | KCNH3 (0.42) | USP2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11642149 | 0.62 | HDAC3 (0.37) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL592164 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |