Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084597 | 0.72 | ALDH1A1 (0.47) | POLBALDH1A1L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3979633 | 0.71 | POLB (0.43) | POLBPGK1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL12856209 | 0.67 | POLB (0.50) | POLBPGK1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5424673 | 0.67 | PIK3CD (0.54) | POLBKMT2ACHRM2MEN1TSHR | |
| SCHEMBL4087810 | 0.66 | TSHR (0.42) | ALDH1A1KMT2AMAPTKDM4EHSD17B10 | |
| SCHEMBL19133223 | 0.65 | APOBEC3A (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL23310509 | 0.64 | KMT2A (0.58) | POLBALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL10481722 | 0.64 | PIK3CD (0.50) | POLBKMT2ACHRM2MEN1TSHR | |
| SCHEMBL4581970 | 0.63 | L3MBTL1 (0.48) | POLBPGK1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL2798224 | 0.63 | SMN1; SMN2 (0.49) | POLBPGK1ALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |