Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084597 | 0.71 | ALDH1A1 (0.47) | TSHRPDE4BHPGDALDH1A1HSD17B10 | |
| SCHEMBL7983584 | 0.68 | PDE4D (0.47) | PDE4DPDE4AALDH1A1KDM4EGAA | |
| SCHEMBL31370999 | 0.68 | KDM4E (0.53) | MAPTKDM4EGAAKMT2AHKDC1 | |
| SCHEMBL3978816 | 0.66 | POLB (0.45) | TSHRMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL3980428 | 0.65 | GAA (0.40) | USP2LMNAPDE4DPDE4BPDE4A | |
| SCHEMBL28756255 | 0.65 | MAPT (0.46) | LMNAMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL22953395 | 0.65 | ACHE (0.45) | PDE4DMAPTKDM4E | |
| SCHEMBL16915008 | 0.64 | HCRTR1 (0.42) | TSHRUSP2PDE4DPDE4BPDE4A | |
| SCHEMBL11635586 | 0.62 | ALOX15 (0.51) | TSHRLMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL1114939 | 0.62 | PDE4D (0.81) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |