Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973213 | 0.81 | HTR2A (0.42) | POLBKMT2ADRD3DRD2SMN1; SMN2 | |
| SCHEMBL4081651 | 0.81 | LMNA (0.46) | ALDH1A1DRD3DRD2KDM4EHSD17B10 | |
| SCHEMBL3974894 | 0.81 | HTR2A (0.44) | POLBKMT2ADRD3DRD2SMN1; SMN2 | |
| SCHEMBL3973796 | 0.80 | HSD17B10 (0.46) | SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL3973494 | 0.80 | IDH1 (0.39) | POLBALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3972272 | 0.78 | CA1 (0.38) | ALDH1A1 | |
| SCHEMBL3973824 | 0.78 | HTR2A (0.36) | ALDH1A1DRD2SMN1; SMN2 | |
| SCHEMBL4084541 | 0.77 | SYK (0.45) | ALDH1A1SMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL3974167 | 0.77 | BCHE (0.39) | DRD3DRD2 | |
| SCHEMBL438402 | 0.77 | HDAC1 (0.42) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |