Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978816 | 0.72 | POLB (0.45) | ALDH1A1KDM4EHPGDL3MBTL1POLB | |
| SCHEMBL4087810 | 0.71 | TSHR (0.42) | ALDH1A1KDM4EHPGDTSHRPDE4B | |
| SCHEMBL3971360 | 0.64 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDRAB9AHTT | |
| SCHEMBL11644099 | 0.63 | HTT (0.46) | HTT | |
| SCHEMBL11635586 | 0.61 | ALOX15 (0.51) | ALDH1A1KDM4ERAB9APOLBTSHR | |
| Ubisindine SCHEMBL191543 | 0.60 | TSHR (0.62) | ALDH1A1KDM4EHPGDRAB9AHTT | |
| SCHEMBL11470635 | 0.60 | MAOA (0.56) | MAOB | |
| SCHEMBL25019712 | 0.59 | MEN1 (0.52) | ALDH1A1KDM4EHPGDL3MBTL1HSD17B10 | |
| SCHEMBL10481175 | 0.59 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDRAB9APOLB | |
| SCHEMBL11385117 | 0.58 | HTR2A (0.51) | ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |