SCHEMBL3979979

SCHEMBL3979979

CCN1CCCC(Cc2ccncc2)C1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.50
PRMT6 Q96LA8 2/20 0.50
HRH3 Q9Y5N1 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP19A1 P11511 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
BCHE P06276 1/20 0.41
MAP4K4 O95819 1/20 0.39
SPR P35270 1/20 0.39
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26233874 0.85 MAOB (0.49) HRH3TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL9912161 0.84 PRMT6 (0.68) CARM1PRMT6CYP1A2CYP3A4BCHE
SCHEMBL20757945 0.83 CARM1 (0.47) CARM1PRMT6HRH3TDP1L3MBTL1
SCHEMBL3978066 0.83 CHRNB2 (0.50) CARM1PRMT6HRH3
SCHEMBL23206055 0.83 HRH3 (0.49) CARM1PRMT6HRH3TDP1L3MBTL1
SCHEMBL13597000 0.79 CYP1A2 (0.49) CYP1A2CYP3A4BCHELMNAPKM
SCHEMBL21605775 0.78 ADRA2B (0.54) CARM1PRMT6BCHELMNA
SCHEMBL16410879 0.76 DRD2 (0.54)
SCHEMBL25625496 0.76 PDE2A (0.45) CARM1PRMT6
SCHEMBL17888494 0.76 CHRM2 (0.48) CARM1PRMT6HRH3TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1607778-B1 Graded index type optical fibres and method of making the same MITSUBISHI RAYON CO (JP) 2009-05-13 EP disclosed
WO-2009056693-A1 NOVEL DERIVATIVES OF N, N'- 2, 4-DIANILINOPYRIMIDINES, PREPARATION THEREOF AS MEDICAMENTS PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS SANOFI-AVENTIS (FR) 2009-05-07 WO disclosed
EP-0942301-B1 GRADED REFRACTIVE INDEX OPTICAL FIBER AND METHOD OF MANUFACTURING THE SAME MITSUBISHI RAYON CO (JP) 2008-02-20 EP disclosed
EP-1607778-A1 Graded index type optical fibres and method of making the same Mitsubishi Rayon Co., Ltd. (JP) 2005-12-21 EP disclosed
US-6631233-B2 Concentrically arranged polymeric layers having decreasing refractive indices MITSUBISHI RAYON CO., LTD. (JP) 2003-10-07 US disclosed
US-20030134119-A1 Graded index polymer optical fiber and a method of making the same GENERAL COMPONENTS, INC. 2003-07-17 US disclosed
US-6307992-B2 Graded index type optical fibers and method of making the same MITSUBISHI RAYON CO., LTD. (JP) 2001-10-23 US disclosed
US-6185353-B1 MULTILAYER STRUCTURE OF CONCENTRICALLY ARRANGED LAYERS CONTAINING A MIXED LAYER OF TWO (CO)POLYMERS OF THE TWO ADJACENT LAYERS FORMED THEREBETWEEN, THE REFRACTIVE INDEX IS HIGHEST AT THE CENTER AND DECREASES TOWARD OUTER PERIPHERY MITSUBISHI RAYON CO., LTD. (JP) 2001-02-06 US disclosed
EP-0942301-A1 DISTRIBUTED REFRACTIVE INDEX OPTICAL FIBER AND METHOD OF MANUFACTURING THE SAME MITSUBISHI RAYON CO., LTD. (JP) 1999-09-15 EP disclosed