SCHEMBL3981589

SCHEMBL3981589

CC1(C)C2CCC1(CS(=O)(=O)ON1C(=O)c3c([N+](=O)[O-])cc4ccccc4c3C1=O)C(=O)C2

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CXCR3 P49682 2/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA5A P35218 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60422 0.83 KMT2A (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL452144 0.79 KMT2A (0.56) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL452153 0.79 CYP1A2 (0.55) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL8968927 0.78 FTO (0.45) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL4545352 0.76 KMT2A (0.50) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL5552230 0.75 KMT2A (0.55) KMT2AMEN1SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL17130615 0.74 CYP1A2 (0.55) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL8756323 0.74 KMT2A (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR
SCHEMBL8907321 0.74 KMT2A (0.56) KMT2AMEN1SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL1133746 0.73 CYP1A2 (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504198-B2 Methods for enhancing resolution of a chemically amplified photoresist ADVANCED MICRO DEVICES, INC. (US) 2009-03-17 US disclosed
US-20070275321-A1 Methods for enhancing resolution of a chemically amplified photoresist ADVANCED MICRO DEVICES, INC. 2007-11-29 US disclosed
US-6566030-B2 Methods and compositions for imaging acids in chemically amplified photoresists using pH-dependent fluorophores YALE UNIVERSITY 2003-05-20 US disclosed
US-20010001698-A1 METHODS AND COMPOSITIONS FOR IMAGING ACIDS IN CHEMICALLY AMPLIFIED PHOTORESISTS USING PH-DEPENDENT FLUOROPHORES ROBERT DAVID GROBER 2001-05-24 US disclosed
EP-0613050-B1 Universal negative tone photoresist IBM (US) 1997-03-26 EP disclosed
EP-0628876-A1 Environmentally stable highly sensitive acid amplifier photoresists International Business Machines Corporation (US) 1994-12-14 EP disclosed
EP-0613050-A2 Universal negative tone photoresist INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-08-31 EP disclosed