Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977299 | 0.82 | FDPS (0.63) | FDPSGGPS1P2RY1P2RX7 | |
| SCHEMBL3982080 | 0.78 | FDPS (0.69) | FDPSGGPS1P2RY1P2RX7 | |
| SCHEMBL3979481 | 0.75 | FDPS (0.49) | FDPSGGPS1P2RY1 | |
| SCHEMBL24476380 | 0.72 | CSNK2A1 (0.37) | P2RX7 | |
| SCHEMBL24476357 | 0.72 | P2RY1 (0.39) | P2RY1 | |
| SCHEMBL24476329 | 0.71 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL24476664 | 0.71 | CSNK2A1 (0.36) | P2RX7 | |
| SCHEMBL24476543 | 0.71 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL22912677 | 0.69 | ADORA2B (0.39) | P2RX7 | |
| SCHEMBL31714921 | 0.69 | P2RX7 (0.34) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |