SCHEMBL279641

SCHEMBL279641

CCCn1c2ccccc2c2cc(N(C)c3ccccc3)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.57
ALDH1A1 P00352 2/20 0.57
CNR2 P34972 5/20 0.46
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
MAPK1 P28482 2/20 0.43
HTT P42858 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
HBB P68871 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NPC1 O15118 1/20 0.43
PGR P06401 1/20 0.42
NPY5R Q15761 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
GAA P10253 1/20 0.41
RORC P51449 2/20 0.41
LMNA P02545 2/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279246 0.92 CNR2 (0.52) HPGDALDH1A1CNR2NPC1PGR
SCHEMBL279090 0.88 MAPT (0.56) HPGDALDH1A1KDM4EMAPTMAPK1
SCHEMBL279539 0.83 GPR3 (0.53) HPGDALDH1A1KDM4EMAPTHTT
SCHEMBL279542 0.82 KDM4E (0.58) HPGDALDH1A1KDM4EMAPTMAPK1
SCHEMBL14465445 0.82 MAPT (0.52) HPGDALDH1A1KDM4EMAPTMAPK1
SCHEMBL14465443 0.80 MAPT (0.55) HPGDALDH1A1KDM4EMAPTMAPK1
SCHEMBL29576546 0.80 RORA (0.50) HPGDALDH1A1CNR2NPC1PGR
SCHEMBL398421 0.80 RORA (0.50) HPGDALDH1A1CNR2NPC1PGR
SCHEMBL13208964 0.80 PTGDR2 (0.47) HPGDALDH1A1KDM4EMAPTHSD17B10
SCHEMBL14465461 0.80 MAPT (0.50) HPGDALDH1A1KDM4EMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-20130306941-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-21 US disclosed
US-8546792-B2 Anthracene derivative, and light emitting element, light emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 US disclosed
US-8546792-B2 Anthracene derivative, and light emitting element, light emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 US disclosed
EP-1918350-A2 Anthracene derivative, and light emitting element, light emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-07 EP disclosed
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-05-01 US disclosed
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-05-01 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080086012-A1 Anthracene Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-10 US disclosed
US-20080086012-A1 Anthracene Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-10 US disclosed
WO-2008038607-A1 ANTHRACENE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-03 WO disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 HPGD 2920/4885ALDH1A1 4/4885CNR2 1945/4885
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 HPGD 2920/4885ALDH1A1 4/4885CNR2 1945/4885
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 HPGD 168/4885ALDH1A1 45/4885CNR2 3023/4885
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative XPOT, XPO1, XPO7 HPGD 168/4885ALDH1A1 45/4885CNR2 3023/4885
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative AMY1A, CYP1A1, CRY1 HPGD 372/4885ALDH1A1 16/4885CNR2 2964/4885
US-20080086012-A1 Anthracene Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Anthracene Derivative GLB1, CYP1A1, XPOT HPGD 196/4885ALDH1A1 55/4885CNR2 3602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.