Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984193 | 0.79 | MAPT (0.50) | HTR2CHTR2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3983803 | 0.77 | HTR2C (0.41) | HTR2CHTR2BERCC1ERCC4KDM4E | |
| SCHEMBL3982744 | 0.77 | TDP1 (0.44) | KDM4EALDH1A1CYP2C9HPGDHSD17B10 | |
| SCHEMBL3985579 | 0.75 | LMNA (0.44) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL13313183 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13271036 | 0.74 | PLAU (0.46) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1634276 | 0.72 | METAP2 (0.48) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10999896 | 0.71 | HTR2C (0.46) | HTR2CHTR2BERCC1ERCC4ALDH1A1 | |
| SCHEMBL574142 | 0.68 | LMNA (0.51) | ALDH1A1CYP3A4HPGDALOX12HIF1A | |
| SCHEMBL8361492 | 0.68 | PDPK1 (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |