Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982744 | 0.88 | TDP1 (0.44) | LMNASMN1; SMN2GAAL3MBTL1PDE10A | |
| SCHEMBL3984193 | 0.84 | MAPT (0.50) | LMNASMN1; SMN2GAAL3MBTL1PDE10A | |
| SCHEMBL3980996 | 0.82 | PTGDR2 (0.39) | LMNAL3MBTL1PTGS2MAPTTSHR | |
| SCHEMBL3984415 | 0.75 | HTR2C (0.43) | LMNASMN1; SMN2GAAL3MBTL1MAPT | |
| SCHEMBL3981435 | 0.72 | PKM (0.46) | LMNASMN1; SMN2PTGS2PDE10AMAPT | |
| SCHEMBL3777437 | 0.72 | PLA2G2A (0.47) | LMNASMN1; SMN2L3MBTL1MAPTTDP1 | |
| SCHEMBL3983651 | 0.70 | PTGDR2 (0.43) | MAPTTSHRTDP1PTGDR2 | |
| SCHEMBL19603072 | 0.70 | MAPT (0.46) | LMNASMN1; SMN2L3MBTL1PDE10AMAPT | |
| SCHEMBL3989567 | 0.69 | LMNA (0.41) | LMNASMN1; SMN2GAAL3MBTL1PTGS2 | |
| SCHEMBL15517314 | 0.68 | LMNA (0.53) | LMNASMN1; SMN2L3MBTL1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |