SCHEMBL398460

SCHEMBL398460

C[C@H](CO)NC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.59
CYP3A4 P08684 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2D6 P10635 2/20 0.58
CYP2C9 P11712 2/20 0.58
CYP2C19 P33261 2/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CTSK P43235 5/20 0.57
CTRB1 P17538 2/20 0.56
ELANE P08246 1/20 0.56
CTSS P25774 6/20 0.54
CTSL P07711 5/20 0.54
CTSB P07858 3/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5268187 1.00 ATM (0.59) ATMCYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL1547277 1.00 ATM (0.59) ATMCYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL15414625 0.88 ATM (0.57) ATMCTSKCTRB1ELANECTSS
SCHEMBL938009 0.88 ATM (0.57) ATMCTSKCTRB1ELANECTSS
SCHEMBL938011 0.88 ATM (0.57) ATMCTSKCTRB1ELANECTSS
SCHEMBL13770419 0.87 CASP3 (0.58) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL13572927 0.87 ATM (0.59) ATMCYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL13534727 0.87 NPC1 (0.65) ATMALDH1A1LMNACTSKCTRB1
SCHEMBL6407665 0.87 ATM (0.59) ATMCYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL14999596 0.87 ATM (0.59) ATMCYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025019172-A1 ANTIMICROBIAL EXTRACTANT FORMED FROM COPPER-CONTAINING SOURCE CORNING INCORPORATED (US) 2025-01-23 WO claimed
US-20260132127-A1 NOVEL SPIRO COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-05-14 US disclosed
US-20260124205-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-07 US disclosed
WO-2026090104-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20260092038-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CORBUS PHARMACEUTICALS INC (US) 2026-04-02 US disclosed
EP-3681875-B1 CYCLIC PEPTIDE ANTIBIOTICS HOFFMANN LA ROCHE (CH) 2026-01-14 EP disclosed
EP-4031542-B1 SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT MERCK SHARP & DOHME LLC (US) 2025-10-15 EP disclosed
US-20250248973-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CORBUS PHARMACEUTICALS, INC. 2025-08-07 US disclosed
EP-4566670-A2 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS Gilead Sciences, Inc. (US) 2025-06-11 EP disclosed
CN-111148739-B Cyclic peptide antibiotics 豪夫迈·罗氏有限公司 2025-06-03 CN disclosed
EP-1307203-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-05-07 EP disclosed
EP-1278502-A2 PROTEASE INHIBITORS SmithKline Beecham Corporation (US) 2003-01-29 EP disclosed
WO-2001089451-A2 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-11-29 WO disclosed
WO-2001070232-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-09-27 WO disclosed
US-6214829-B1 NERVOUS SYSTEM, PSYCHOLOGICAL DISORDERS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 2001-04-10 US disclosed
EP-0900792-A1 Piperazine and piperidine derivatives as 5-HT1 receptor agonists DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1999-03-10 EP disclosed
US-5688823-A ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS SANKYO COMPANY, LIMITED (JP) 1997-11-18 US disclosed
US-5578620-A TREATMENT OF DIABETES AND HYPERLIPEMIA SANKYO COMPANY, LIMITED (JP) 1996-11-26 US disclosed
EP-0678511-A2 Thiazolidine and oxazolidine derivatives, their preparation and their medical use SANKYO COMPANY LIMITED (JP) 1995-10-25 EP disclosed
US-3971822-A Aspartyl amide sweetening agents TANABE SEIYAKU CO., LTD. (JA) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250248973-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CNR1, CNR2, GPR119 ATM 2968/4885CYP3A4 1597/4885CYP1A2 1105/4885
US-20260124205-A1 MODULATORS OF BETA CATENIN AND USES THEREOF CTNNB1, CTNNA1, CTNND1 ATM 4266/4885CYP3A4 2366/4885CYP1A2 3433/4885
US-20260092038-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CNR1, CNR2, GPR119 ATM 2937/4885CYP3A4 1408/4885CYP1A2 1384/4885
US-20260132127-A1 NOVEL SPIRO COMPOUND TRHR, NR3C2, THRB ATM 2868/4885CYP3A4 4152/4885CYP1A2 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.