SCHEMBL3984623

SCHEMBL3984623

C[C@@H](NO)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.48
▸ HSD17B10 Q99714 3/20 0.48
▸ APAF1 O14727 1/20 0.48
▸ CYP3A4 P08684 3/20 0.48
▸ CHRM2 P08172 2/20 0.48
▸ ADRA1A P35348 2/20 0.48
▸ CYP2D6 P10635 2/20 0.48
▸ CYP2C19 P33261 2/20 0.48
▸ LMNA P02545 2/20 0.48
▸ HTR1A P08908 1/20 0.48
▸ ADRA2A P08913 1/20 0.48
▸ ADORA3 P0DMS8 1/20 0.48
▸ CHRM1 P11229 1/20 0.48
▸ SMPD1 P17405 1/20 0.48
▸ DRD1 P21728 1/20 0.48
▸ TBXA2R P21731 1/20 0.48
▸ SLC6A2 P23975 1/20 0.48
▸ SLC6A4 P31645 1/20 0.48
▸ OPRM1 P35372 1/20 0.48
▸ DRD3 P35462 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984108 1.00 TDP1 (0.48) TDP1HSD17B10APAF1CYP3A4CHRM2
SCHEMBL3044206 1.00 TDP1 (0.48) TDP1HSD17B10APAF1CYP3A4CHRM2
Hydrochloric Acid SCHEMBL8783045 0.97 MEN1 (0.50) TDP1HSD17B10APAF1CYP3A4CHRM2
SCHEMBL9641540 0.81 ALOX5 (0.52) KCNH2ACP3ALDH1A1
SCHEMBL283979 0.78 SIGMAR1 (0.61) HSD17B10APAF1CYP3A4CHRM2ADRA1A
SCHEMBL28869351 0.78 CYP3A4 (0.52) HSD17B10APAF1CYP3A4CHRM2ADRA1A
SCHEMBL30763462 0.78 SIGMAR1 (0.61) HSD17B10APAF1CYP3A4CHRM2ADRA1A
SCHEMBL1200137 0.78 SIGMAR1 (0.61) HSD17B10APAF1CYP3A4CHRM2ADRA1A
SCHEMBL8437895 0.78 SIGMAR1 (0.61) HSD17B10APAF1CYP3A4CHRM2ADRA1A
SCHEMBL2390659 0.78 CYP3A4 (0.52) HSD17B10APAF1CYP3A4CHRM2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118516915-A Longitudinal connection analysis method and design for bridge concrete anti-collision guardrail 陕西省交通规划设计研究院有限公司 2024-08-20 — — CN claimed
CN-118308960-A Vertical connecting structure of bridge concrete anti-collision guardrail and strength calculation method thereof 北京中交华安科技有限公司 2024-07-09 — — CN claimed
CN-118295006-A System for calibrating DDL-1 type gas radon instrument based on AlphaGUARD P F radon instrument 云南省地震局信息中心 2024-07-05 — — CN claimed
CN-216132780-U Diffusion type sampling emanometer response capability testing device 赵影 2022-03-25 — — CN claimed
US-8084630-B2 Process for the synthesis of ramelteon and its intermediates TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2011-12-27 — — US claimed
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-11-12 — — US claimed
EP-2098519-A1 Process for the synthesis of ramelteon and its intermediates Teva Pharmaceutical Industries Ltd. (IL) 2009-09-09 — — EP claimed
EP-2069320-A2 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES Teva Pharmaceutical Industries Ltd. (IL) 2009-06-17 — — EP claimed
WO-2009056993-A2 A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-05-07 — — WO claimed
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-03-12 — — US claimed
WO-2008151170-A2 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2008-12-11 — — WO claimed
US-20250188325-A1 POSITIVELY CHARGED ADHESIVES THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2025-06-12 — — US disclosed
CN-118795532-A Moisture-flow-resistant radon source and preparation method and application thereof 上海市计量测试技术研究院(中国上海测试中心、华东国家计量测试中心、上海市计量器具强制检定中心) 2024-10-18 — — CN disclosed
CN-118759573-A Gas-flowing radon source and application thereof 上海市计量测试技术研究院(中国上海测试中心、华东国家计量测试中心、上海市计量器具强制检定中心) 2024-10-11 — — CN disclosed
US-20240321472-A1 REMOVING A RADIOACTIVE NOBLE GAS FROM A GAS VOLUME SCK CEN (BE) 2024-09-26 — — US disclosed
EP-2069320-A2 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES Teva Pharmaceutical Industries Ltd. (IL) 2009-06-17 — — EP disclosed
WO-2009056993-A2 A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-05-07 — — WO disclosed
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-03-12 — — US disclosed
WO-2008151170-A2 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2008-12-11 — — WO disclosed
US-20060020004-A1 Isoxazolidine compounds for treatment of bacterial infections INFINITY PHARMACEUTICALS, INC. (US) 2006-01-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 TDP1 2994/4885HSD17B10 146/4885APAF1 4833/4885
US-20060020004-A1 Isoxazolidine compounds for treatment of bacterial infections QDPR, NQO2, SQLE TDP1 2846/4885HSD17B10 3222/4885APAF1 2628/4885
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 TDP1 2771/4885HSD17B10 204/4885APAF1 4852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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