Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168323 | 0.76 | OPRM1 (0.39) | OPRM1OPRK1KCNH2OPRD1HRH3 | |
| SCHEMBL3183048 | 0.72 | OPRM1 (0.38) | OPRM1OPRK1KCNH2OPRD1HRH3 | |
| SCHEMBL5221409 | 0.72 | OPRM1 (0.37) | OPRM1OPRK1KCNH2CHRM1 | |
| SCHEMBL3176047 | 0.71 | DRD2 (0.38) | OPRM1OPRK1KCNH2CHRM1CYP2D6 | |
| SCHEMBL13394866 | 0.71 | DRD2 (0.38) | OPRM1OPRK1KCNH2CHRM1CYP2D6 | |
| SCHEMBL3987447 | 0.70 | OPRM1 (0.46) | OPRM1OPRK1KCNH2OPRD1CHRM1 | |
| SCHEMBL3167461 | 0.68 | OPRM1 (0.35) | OPRM1OPRK1KCNH2OPRD1HRH3 | |
| SCHEMBL5507817 | 0.64 | L3MBTL1 (0.51) | HRH3CYP2D6KMT2APARP1 | |
| SCHEMBL3168029 | 0.64 | OPRM1 (0.39) | OPRM1OPRK1KCNH2OPRD1CHRM1 | |
| SCHEMBL13394765 | 0.64 | OPRM1 (0.39) | OPRM1OPRK1KCNH2OPRD1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833826-B1 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-27 | — | — | EP | disclosed |