Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 6/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435744 | 0.77 | KIF11 (0.50) | KIF11 | |
| SCHEMBL3537438 | 0.76 | RXRA (0.50) | NOTUMRXRARXRBRXRGKIF11 | |
| SCHEMBL3991060 | 0.76 | CES2 (0.40) | — | |
| SCHEMBL1436093 | 0.75 | RXRA (0.40) | RXRARXRBRXRG | |
| SCHEMBL744561 | 0.75 | SCN2A (0.49) | NOTUMKIF11 | |
| SCHEMBL745572 | 0.74 | — | — | |
| SCHEMBL3991110 | 0.74 | TRPA1 (0.35) | — | |
| SCHEMBL745447 | 0.73 | CYP11B2 (0.40) | NOTUMCYP11B2CYP11B1 | |
| SCHEMBL1435816 | 0.72 | TRPA1 (0.43) | NOTUMAR | |
| SCHEMBL3996802 | 0.72 | AR (0.36) | NOTUMCYP11B2CYP11B1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| EP-2064190-A1 | PYRIMIDYLMETHYL-SULFONAMIDE COMPOUNDS USEFUL AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008062011-A1 | PYRIMIDYLMETHYL-SULFONAMIDE COMPOUNDS USEFUL AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |