Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.44 |
| ▸ | ADK | P55263 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453483 | 0.77 | MAPK1 (0.46) | SLC29A1ADKHIF1ATP53ADORA2A | |
| SCHEMBL453482 | 0.77 | MAPK1 (0.46) | SLC29A1ADKHIF1ATP53ADORA2A | |
| SCHEMBL6702778 | 0.72 | HIF1A (0.42) | SLC29A1ADKHIF1ATP53ADORA2A | |
| SCHEMBL8805090 | 0.71 | CDK5 (0.41) | SLC29A1ADKHIF1ATP53ADORA2A | |
| SCHEMBL3841527 | 0.71 | DOT1L (0.50) | SLC29A1ADKHIF1ATP53ADORA2A | |
| SCHEMBL27767961 | 0.71 | DOT1L (0.50) | SLC29A1ADKHIF1ATP53ADORA2A | |
| SCHEMBL7744286 | 0.71 | ALDH1A1 (0.39) | SLC29A1HIF1ATP53ADORA2AADORA1 | |
| SCHEMBL9243746 | 0.71 | ADORA1 (0.39) | ADKHIF1ATP53ADORA1CYP1A2 | |
| SCHEMBL29267975 | 0.70 | SLC29A1 (0.42) | SLC29A1HIF1ATP53ADORA2AADORA3 | |
| SCHEMBL3989523 | 0.70 | SLC29A1 (0.45) | SLC29A1ADKHIF1ATP53ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061316-A2 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VARIAL POLYMERASES | Southern Research Institute (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008067002-A2 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VARIAL POLYMERASES | SOUTHERN RESEARCH INSTITUTE (US) | 2008-06-05 | — | — | WO | claimed |