Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980812 | 0.72 | ALDH1A1 (0.44) | MAPK1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3985590 | 0.71 | CCNE2 (0.47) | MAPK1ALDH1A1HPGDMAPTTSHR | |
| SCHEMBL3984739 | 0.69 | LMNA (0.38) | MAPK1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4300214 | 0.66 | MAPK1 (0.53) | MAPK1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3984193 | 0.64 | MAPT (0.50) | MAPK1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL25328584 | 0.63 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL3980996 | 0.61 | PTGDR2 (0.39) | MAPK1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL14919774 | 0.61 | PDE4D (0.38) | MAPK1ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL2871982 | 0.61 | MAPT (0.57) | ALDH1A1MAPTLMNAKMT2AL3MBTL1 | |
| SCHEMBL16680513 | 0.60 | PPARG (0.46) | MAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |