Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983651 | 0.89 | PTGDR2 (0.43) | PTGDR2MAPTTSHRTDP1 | |
| SCHEMBL3980812 | 0.85 | ALDH1A1 (0.44) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL3985579 | 0.82 | LMNA (0.44) | PTGDR2PTGDRPTGS2MAPTLMNA | |
| SCHEMBL3981435 | 0.77 | PKM (0.46) | PTGDR2PTGDRPTGS2MAPTLMNA | |
| SCHEMBL3983803 | 0.76 | HTR2C (0.41) | MAPTKDM4EKMT2AMAPK1L3MBTL1 | |
| SCHEMBL3989567 | 0.74 | LMNA (0.41) | PTGDR2PTGDRPTGS2MAPTLMNA | |
| SCHEMBL3985878 | 0.71 | PTGDR (0.51) | PTGDR2PTGDRPTGS2MAPTLMNA | |
| SCHEMBL3982744 | 0.70 | TDP1 (0.44) | PTGDR2MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL3778420 | 0.70 | KDM4E (0.43) | PTGDR2PTGDRPTGS2MAPTLMNA | |
| SCHEMBL3783447 | 0.70 | PTGDR2 (0.43) | PTGDR2PTGDRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |