Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153422 | 0.81 | PKM (0.74) | KDM4EKMT2APKMLMNAGAA | |
| SCHEMBL29452815 | 0.81 | PKM (0.74) | KDM4EKMT2APKMLMNAGAA | |
| SCHEMBL3981435 | 0.81 | PKM (0.46) | KDM4EKMT2APKMLMNASMN1; SMN2 | |
| SCHEMBL341900 | 0.77 | LMNA (0.54) | KDM4EKMT2APKMLMNAGAA | |
| SCHEMBL5000233 | 0.76 | LMNA (0.55) | KDM4EKMT2APKMLMNAGAA | |
| SCHEMBL28587779 | 0.75 | KDM4E (0.51) | KDM4EKMT2APKMLMNAGAA | |
| SCHEMBL3987954 | 0.73 | LMNA (0.52) | KDM4EKMT2ALMNAGAASMN1; SMN2 | |
| SCHEMBL3989567 | 0.73 | LMNA (0.41) | KDM4EKMT2APKMLMNAGAA | |
| SCHEMBL342560 | 0.72 | KDM4E (0.47) | KDM4EKMT2APKMLMNATSHR | |
| SCHEMBL6643516 | 0.71 | LMNA (0.43) | KDM4EKMT2ALMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |