SCHEMBL1153422

SCHEMBL1153422

COC(=O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.74
KDM4E B2RXH2 9/20 0.63
CYP3A4 P08684 1/20 0.63
ALOX12 P18054 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
GAA P10253 1/20 0.62
MAPT P10636 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
HSP90AA1 P07900 1/20 0.52
CCR6 P51684 1/20 0.52
ALDH1A1 P00352 3/20 0.51
KMT2A Q03164 3/20 0.51
HSD17B10 Q99714 2/20 0.51
MEN1 O00255 1/20 0.51
CGAS Q8N884 1/20 0.49
NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452815 1.00 PKM (0.74) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL342559 0.87 PKM (0.67) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL29514385 0.87 PKM (0.67) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL17859581 0.86 PKM (0.74) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL9134176 0.86 PKM (0.66) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL342125 0.86 PKM (0.66) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL30026873 0.86 PKM (0.66) PKMKDM4ECYP3A4ALOX12TDP1
Dimethylamine SCHEMBL19690796 0.85 PKM (0.77) PKMKDM4ECYP3A4ALOX12TDP1
Dimethylamine SCHEMBL15437599 0.85 PKM (0.77) PKMKDM4ECYP3A4ALOX12TDP1
SCHEMBL13492293 0.85 PKM (0.54) PKMKDM4ECYP3A4ALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115970622-A Method and system for chemically synthesizing cloquintocet-mexyl 新沂市永诚化工有限公司 2023-04-18 CN claimed
CN-113461610-A Preparation process and preparation system of cloquintocet-mexyl 新沂市永诚化工有限公司 2021-10-01 CN claimed
CN-113121431-A Method for chemically synthesizing cloquintocet-mexyl 新沂市永诚化工有限公司 2021-07-16 CN claimed
EP-1606254-B1 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS BAYER CROPSCIENCE AG (DE) 2011-05-11 EP claimed
US-20110092368-A1 2,4,6-Phenyl-substituted cyclic ketoenols FISCHER REINER 2011-04-21 US claimed
US-7888285-B2 2,4,6-phenyl substituted cyclic ketoenols BAYER CROPSCIENCE AG (DE) 2011-02-15 US claimed
US-20070015664-A1 2,4,6-Phenyl substituted cyclic ketoenols BAYER CROPSCIENCE AG (DE) 2007-01-18 US claimed
US-7115543-B2 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER CROPSCIENCE AG (DE) 2006-10-03 US claimed
US-20060160703-A1 Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners BAYER CROPSCIENCE AG (DE) 2006-07-20 US claimed
EP-1303189-B1 ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES BAYER CROPSCIENCE AG (DE) 2005-08-24 EP claimed
US-20050009705-A1 Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-13 US claimed
US-20040132619-A1 Selective substituted aryl ketone and safener based herbicides BAYER CROPSCIENCE K.K. (JP) 2004-07-08 US claimed
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-13 US claimed
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2026-05-28 US disclosed
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2026-05-21 US disclosed
US-12599136-B2 Substituted isophthalic acid diamides and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2026-04-14 US disclosed
US-20020115569-A1 Herbicidal composition AVENTIS CROPSCIENCE GMBH (DE) 2002-08-22 US disclosed
US-20020091066-A1 Herbicidal compositions BAYER CROPSCIENCE GMBH (DE) 2002-07-11 US disclosed
CN-1318978-A Herbicidal compositions containing substituted phenoxysulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2001-10-24 CN disclosed
CN-1312680-A Herbicidal compositions containing acylated aminophenylsulfonylureas AVENTIES CROP SCIENCES GMBH (DE) 2001-09-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES CBR1, CBR3, HDHD5 PKM 1938/4885KDM4E 3156/4885CYP3A4 2286/4885
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS FOXM1, CSDE1, RCC1 PKM 3598/4885KDM4E 1585/4885CYP3A4 304/4885
US-20070015664-A1 2,4,6-Phenyl substituted cyclic ketoenols CYP4X1, KDM4E, KCNE1 PKM 7/4885KDM4E 2/4885CYP3A4 58/4885
US-20110092368-A1 2,4,6-Phenyl-substituted cyclic ketoenols CYP4X1, KDM4E, PDHX PKM 6/4885KDM4E 2/4885CYP3A4 35/4885
US-20020091066-A1 Herbicidal compositions CBR1, CBR3, GLRA1 PKM 4319/4885KDM4E 3026/4885CYP3A4 1060/4885
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides AADAC, CBR3, ABAT PKM 921/4885KDM4E 1867/4885CYP3A4 810/4885
US-20040132619-A1 Selective substituted aryl ketone and safener based herbicides CYP2W1, CYP4Z1, CYP2E1 PKM 450/4885KDM4E 1001/4885CYP3A4 54/4885
US-20050009705-A1 Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners TARS2, TST, DDT PKM 1520/4885KDM4E 2555/4885CYP3A4 173/4885
US-20060160703-A1 Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners DDT, DDX41, DDC PKM 1425/4885KDM4E 627/4885CYP3A4 157/4885
US-12599136-B2 Substituted isophthalic acid diamides and their use as herbicides P4HA1, DDT, CNPY2 PKM 3574/4885KDM4E 2659/4885CYP3A4 2135/4885
US-20020115569-A1 Herbicidal composition CBR1, DDT, CYP1A1 PKM 4145/4885KDM4E 3552/4885CYP3A4 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.