Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 3/20 | 0.52 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | ARRB1 | P49407 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922209 | 0.84 | ALDH1A1 (0.57) | IP6K1DDR1KDM4EALDH1A1 | |
| SCHEMBL16380773 | 0.84 | IP6K1 (0.56) | IP6K1DDR1KDM4EALDH1A1TP53 | |
| SCHEMBL3997899 | 0.83 | KDM4E (0.52) | KDM4EALOX15HTTALDH1A1MAPK1 | |
| SCHEMBL3919981 | 0.82 | NPSR1 (0.62) | DDR1KDM4EALOX15HTTALDH1A1 | |
| SCHEMBL3916828 | 0.82 | ALDH1A1 (0.51) | KDM4EALOX15HTTALDH1A1NPSR1 | |
| SCHEMBL2906362 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1GAA | |
| SCHEMBL4264923 | 0.79 | CYP2A13 (0.62) | IP6K1ALOX15ALDH1A1 | |
| SCHEMBL13861948 | 0.74 | SMN1; SMN2 (0.48) | KDM4EALOX15HTTALDH1A1NPSR1 | |
| SCHEMBL19192738 | 0.72 | ALDH1A1 (0.58) | DDR1KDM4EALDH1A1 | |
| SCHEMBL4889004 | 0.72 | ALDH1A1 (0.58) | IP6K1DDR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038253-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | Arrow Therapeutics Limited (GB) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007138242-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2007-12-06 | — | — | WO | disclosed |