Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751443 | 0.76 | CYP2C19 (0.35) | ALDH1A1SMN1; SMN2TSHRKDM4ETDP1 | |
| SCHEMBL3789477 | 0.72 | CYP2C19 (0.40) | ALDH1A1SMN1; SMN2GAATSHRKDM4E | |
| SCHEMBL27530901 | 0.70 | LTA4H (0.41) | ALDH1A1SMN1; SMN2GAALTA4HTSHR | |
| SCHEMBL7706278 | 0.70 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2GAATSHRKDM4E | |
| SCHEMBL28821829 | 0.69 | CTSK (0.38) | EBPSIGMAR1MEN1 | |
| SCHEMBL3398385 | 0.67 | KIF11 (0.59) | LTA4HTSHRTDP1L3MBTL1 | |
| SCHEMBL6421194 | 0.67 | LTA4H (0.47) | ALDH1A1LTA4HTSHRTDP1L3MBTL1 | |
| SCHEMBL28059566 | 0.66 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2ATM | |
| SCHEMBL11878904 | 0.66 | LTA4H (0.43) | ALDH1A1SMN1; SMN2LTA4HTSHRTDP1 | |
| SCHEMBL5738523 | 0.66 | EBP (0.33) | LTA4HEBPSIGMAR1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069797-A2 | METHODS FOR ANALYSING PROTEIN SAMPLES BASED ON THE IDENTIFICATION OF C-TERMINAL PEPTIDES | Koninklijke Philips Electronics N.V. (NL) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008032235-A2 | METHODS FOR ANALYSING PROTEIN SAMPLES BASED ON THE IDENTIFICATION OF C-TERMINAL PEPTIDES | KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) | 2008-03-20 | — | — | WO | disclosed |