Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044616 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTPTGER2MEN1 | |
| SCHEMBL27452301 | 0.94 | PTGER2 (0.53) | ALDH1A1MAPTHTTPTGER2MEN1 | |
| SCHEMBL639304 | 0.92 | MAPT (0.49) | ALDH1A1MAPTHTTPTGER2MEN1 | |
| SCHEMBL639305 | 0.92 | MAPT (0.49) | ALDH1A1MAPTHTTPTGER2MEN1 | |
| SCHEMBL8898411 | 0.87 | CA12 (0.43) | ALDH1A1MAPTHTTPTGER2PPARG | |
| SCHEMBL7149177 | 0.86 | MAPT (0.47) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL13764875 | 0.84 | MMP1 (0.47) | ALDH1A1MAPTHTTTSHRCA12 | |
| SCHEMBL29117963 | 0.83 | HTT (0.45) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL6829910 | 0.83 | MEN1 (0.50) | ALDH1A1MAPTHTTPTGER2MEN1 | |
| SCHEMBL8770971 | 0.81 | HTT (0.59) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138276-A | Synthesis method of chiral 5- (4-fluorophenyl) -5-hydroxypentanoate | 郑州手性药物研究院有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-102605034-B | Biological enzyme resolution method for preparing optically pure (S)-5-(4-fluorophenyl)-5-hydroxypentanoate | CHONGQING HUIJIAN BIOLOG TECHNOLOGY CO LTD | 2014-05-14 | — | — | CN | claimed |
| CN-102605034-A | Biological enzyme resolution method for preparing optically pure (S)-5-(4-fluorophenyl)-5-hydroxypentanoate | CHONGQING HUIJIAN BIOLOG TECHNOLOGY CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-111138276-A | Synthesis method of chiral 5- (4-fluorophenyl) -5-hydroxypentanoate | 郑州手性药物研究院有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-111138276-A | Synthesis method of chiral 5- (4-fluorophenyl) -5-hydroxypentanoate | 郑州手性药物研究院有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-103896700-A | Preparation method of ezetimibe chiral intermediate | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-102605034-B | Biological enzyme resolution method for preparing optically pure (S)-5-(4-fluorophenyl)-5-hydroxypentanoate | CHONGQING HUIJIAN BIOLOG TECHNOLOGY CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-101384532-B | method for producing optically active alcohol | KOTOBUKI PHARMACEUTICAL CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-102605034-A | Biological enzyme resolution method for preparing optically pure (S)-5-(4-fluorophenyl)-5-hydroxypentanoate | CHONGQING HUIJIAN BIOLOG TECHNOLOGY CO LTD | 2012-07-25 | — | — | CN | disclosed |
| CN-100582092-C | Process for preparing diphenyl azetidinone derivatives | AVENTIS PHARMA GMBH | 2010-01-20 | — | — | CN | disclosed |
| US-7563888-B2 | Process for the preparation of diphenyl azetidinone derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-07-21 | — | — | US | disclosed |
| CN-101384532-A | Method for producing optically active alcohol | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| US-20070149501-A1 | PROCESS FOR THE PREPARATION OF DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| CN-1956951-A | Method for producing diphenyl azetidinone derivatives | AVENTIS PHARMA GMBH (DE) | 2007-05-02 | — | — | CN | disclosed |
| CN-1268889-A | Novel process for obtg. intermediates | SMITHKLINE BEECHAM CORP (US) | 2000-10-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149501-A1 | PROCESS FOR THE PREPARATION OF DIPHENYL AZETIDINONE DERIVATIVES | CYP46A1, APOB, DHCR7 | ALDH1A1 881/4885MAPT 4766/4885HTT 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.