Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998431 | 0.88 | LMNA (0.40) | ALDH1A1LMNAUSP2TSHRHTT | |
| SCHEMBL4003849 | 0.88 | ACHE (0.41) | ALDH1A1GAAMEN1KMT2AACHE | |
| SCHEMBL4000459 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDMAPK1CYP2C9 | |
| SCHEMBL3013804 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAUSP2TSHRHTT | |
| SCHEMBL3013194 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAUSP2TSHRHTT | |
| SCHEMBL4000382 | 0.81 | GRIN1 (0.48) | ALDH1A1LMNAUSP2TSHRHTT | |
| SCHEMBL4001686 | 0.79 | MAPT (0.42) | ALDH1A1LMNAUSP2TSHRHTT | |
| SCHEMBL4002432 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRHPGDMEN1 | |
| SCHEMBL2998041 | 0.76 | NPC1 (0.40) | ALDH1A1LMNAHPGDMAPK1CYP2C9 | |
| SCHEMBL3999096 | 0.76 | ACHE (0.41) | ALDH1A1GAAMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |